Volume 24, No 10, Oct 2014
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 24 Issue 10, October 2014: 1159-1161
RESEARCH HIGHLIGHTS
Regeneration: making muscle from hPSCs
Xiping Zhu1,*, Lina Fu1,*, Fei Yi2,*, Guang-Hui Liu1,3, Alejandro Ocampo2, Jing Qu4,5 and Juan Carlos Izpisua Belmonte2
1National Laboratory of Biomacromolecules, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
2Gene Expression Laboratory, Salk Institute for Biological Studies, 10010 North Torrey Pines Road, La Jolla, CA 92037, USA
3Beijing Institute for Brain Disorders, Beijing 100069, China
4Key Laboratory of Non-coding RNA, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
5Laboratory of RNA Biology, Institute of Biophysics, Chinese Academy of Sciences, Beijing 100101, China
Correspondence: Jing Qu,Juan Carlos Izpisua Belmonte(jqu@moon.ibp.ac.cn ,belmonte@salk.edu)
In recent years, researchers worldwide have developed protocols to efficiently differentiate skeletal myogenic cells from human pluripotent stem cells through either ectopic gene expression or the use of small molecules. These stem cell-derived myogenic cells provide new avenues for the study of muscle-related diseases, drug screening and are potentially a new tool for cell therapy against muscular dystrophies.
10.1038/cr.2014.91
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