Volume 24, No 11, Nov 2014

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 24 Issue 11, November 2014: 1284-1285

RESEARCH HIGHLIGHTS

Expanding the functional role of long noncoding RNAs

Per Johnsson¹ and Kevin V Morris^2,3

¹Department of Oncology and Pathology, Karolinska Institutet, SE-171 77 Stockholm, Sweden
²Biotechnology and Biomedical Sciences, The University of New South Wales, NSW 2052, Sydney, Australia
³Department of Molecular and Experimental Medicine, The Scripps Research Institute, La Jolla, CA 92037, USA Correspondence: Kevin V Morris,(kmorris@unsw.edu.au)

New findings bring to light a previously unappreciated mechanism involved in the regulation of the oncoprotein MYC. Interesting observations find that the long noncoding RNA (lncRNA) PVT1 is active in controlling levels of MYC through regulation of MYC protein stability.

10.1038/cr.2014.104

FULL TEXT | PDF

Browse 1638