Volume 24, No 12, Dec 2014

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 24 Issue 12, December 2014: 1379-1380

RESEARCH HIGHLIGHTS

Producing GM-CSF: a unique T helper subset?

Dietmar Herndler-Brandstetter¹ and Richard A Flavell^1,2

¹Department of Immunobiology, Yale University School of Medicine, New Haven, CT 06520, USA
²Howard Hughes Medical Institute, Yale University School of Medicine, New Haven, CT 06520, USA Correspondence: Richard A Flavell,(Richard.flavell@yale.edu)

GM-CSF-producing helper T cells have previously been identified to serve a nonredundant function in the initiation of autoimmune inflammation. An article by Sheng et al. recently published by Cell Research now suggests that the differentiation program of GM-CSF-producing cells from naïve CD4+ T cells is distinct from that of Th1 and Th17 cells, and is regulated by the IL-7-STAT5 axis.

10.1038/cr.2014.155

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