Volume 25, No 1, Jan 2015

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 25 Issue 1, January 2015: 5-6

RESEARCH HIGHLIGHTS

Choreography of AMPK activation

Christopher G Langendorf¹ and Bruce E Kemp¹

¹St Vincent's Institute & Department of Medicine, The University of Melbourne, 41 Victoria Parade, Fitzroy, Victoria 3065, Australia Correspondence: Bruce E Kemp,(bkemp@svi.edu.au)

A recent study published in Cell Research by Li and colleagues reports a detailed biophysical and structural study of AMPK's intra-molecular interactions during activation. By employing subunit tagging and proximity analysis with the aid of AlphaScreen instrumentation, Li et al. add to our understanding of the choreography of activation of AMPK by both nucleotides and phosphorylation.

10.1038/cr.2014.163

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