Volume 25, No 1, Jan 2015
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 25 Issue 1, January 2015: 1-2
RESEARCH HIGHLIGHTS
Migrasomes: a new organelle of migrating cells
Bruno da Rocha-Azevedo1,2 and Sandra L Schmid1
1Department of Cell Biology, University of Texas Southwestern Medical Center, Dallas, Texas, USA
2Federal University of Rio de Janeiro, Rio de Janeiro, Brazil
Correspondence: Sandra L Schmid,(sandra.schmid@utsouthwestern.edu)
Cell migration is a multi-step process that involves the coordinated action of signaling networks, cytoskeletal dynamics and vesicular trafficking, leading to protrusion and adhesion at the leading edge of cells and contraction and detachment at their rear. In a recent paper in Cell Research, Ma et al. describe the biogenesis of a new exosome-like organelle — named migrasomes — that derive from retraction fibers at the rear of migrating cells and their potential roles in inter-cellular signaling.
10.1038/cr.2014.146
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