Volume 25, No 7, Jul 2015
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 25 Issue 7, July 2015: 765-766
RESEARCH HIGHLIGHTS
Promoting metastasis: neutrophils and T cells join forces
Zvi G Fridlender1, Steven M Albelda2 and Zvi Granot3
1Institute of Pulmonary Medicine, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, Israel
2Thoracic Oncology Research Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
3Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel Canada, Hebrew University Medical School, 91120 Jerusalem, Israel
Correspondence: Zvi Granot, E-mail: zvikag@ekmd.huji.ac.il; Steven M Albelda, E-mail: albelda@mail.med.upenn.edu; Zvi G Fridlender, E-mail:(Fridlender@Hadassah.org.il)
The role neutrophils play in cancer is a matter of debate as both pro- and anti-tumor functions have been documented. In a recent publication in Nature, Coffelt et al. identify a new mechanism where neutrophils and T cells cooperate to generate metastasis-supporting immune suppression.
10.1038/cr.2015.62
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