Volume 25, No 7, Jul 2015

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 25 Issue 7, July 2015: 765-766

RESEARCH HIGHLIGHTS

Promoting metastasis: neutrophils and T cells join forces

Zvi G Fridlender¹, Steven M Albelda² and Zvi Granot³

¹Institute of Pulmonary Medicine, Hadassah-Hebrew University Medical Center, 91120 Jerusalem, Israel
²Thoracic Oncology Research Laboratory, University of Pennsylvania, Philadelphia, PA 19104, USA
³Department of Developmental Biology and Cancer Research, Institute for Medical Research Israel Canada, Hebrew University Medical School, 91120 Jerusalem, Israel Correspondence: Zvi Granot, E-mail: zvikag@ekmd.huji.ac.il; Steven M Albelda, E-mail: albelda@mail.med.upenn.edu; Zvi G Fridlender, E-mail:(Fridlender@Hadassah.org.il)

The role neutrophils play in cancer is a matter of debate as both pro- and anti-tumor functions have been documented. In a recent publication in Nature, Coffelt et al. identify a new mechanism where neutrophils and T cells cooperate to generate metastasis-supporting immune suppression.

10.1038/cr.2015.62

FULL TEXT | PDF

Browse 1916