Volume 25, No 9, Sep 2015

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 25 Issue 9, September 2015: 989-990

RESEARCH HIGHLIGHTS

Dendritic cells are stressed out in tumor

Tomasz Maj¹ and Weiping Zou^1,2,3

¹Department of Surgery, University of Michigan School of Medicine, Ann Arbor, MI 48109, USA
²Graduate Programs in Immunology and Tumor Biology, University of Michigan, Ann Arbor, MI 48109, USA
³The University of Michigan Comprehensive Cancer Center, University of Michigan, Ann Arbor, MI 48109, USA Correspondence: Weiping Zou,(wzou@med.umich.edu)

A recently paper published in Cell reports that dendritic cells (DCs) are dysfunctional in the tumor environment. Tumor impairs DC function through induction of endoplasmic reticulum stress response and subsequent disruption of lipid metabolic homeostasis.

10.1038/cr.2015.93

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