Volume 25, No 12, Dec 2015

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 25 Issue 12, December 2015: 1279-1280

RESEARCH HIGHLIGHTS

Detecting hepatocellular carcinoma in blood

Lulu Hu^1,2 and Chuan He^1,2

¹Department of Chemistry, Department of Biochemistry and Molecular Biology, and Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA
²Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA Correspondence: Chuan He,(chuanhe@uchicago.edu)

Liquid biopsy is ideal for early diagnosis of cancer and for prognosis upon treatment. Lu et al. describe a methylated CpG tandems amplification and sequencing method to profile hypermethylated CpG islands genome-widely in cell-free DNA, and further identify high performance markers in blood for potential detection of early stage hepatocellular carcinoma.

10.1038/cr.2015.136

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