Volume 26, No 2, Feb 2016

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 26 Issue 2, February 2016: 145-146

RESEARCH HIGHLIGHTS

Master and commander: epigenetic regulation of macrophages

Mihai G Netea¹ and Leo AB Joosten¹

¹Department of Internal Medicine and Radboud Center for Infectious Diseases (RCI), Radboud University Medical Center, Nijmegen, The Netherlands Correspondence: E-mail: mihai.netea@radboudumc.nl; Leo AB Joosten,(leo.joosten@radboudumc.nl)

Macrophages are important innate immune cells with functions in tissue repair and remodeling, induction and resolution of inflammation, as well as elimination of invading pathogens. In a recent study, Schmidt and colleagues describe the open epigenetic landscape of the human inflammatory macrophages, and the transcriptional regulators responsible for their rapid response to environmental signals.

10.1038/cr.2016.5

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