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Volume 26, No 6, Jun 2016

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 26 Issue 6, June 2016: 641-642

RESEARCH HIGHLIGHTS

ESCRT machinery: Damage control at the nuclear membrane

Leandro N Ventimiglia1 and Juan Martin-Serrano1

1Department of Infectious Diseases, King's College London, London SE1 9RT, UK Correspondence: Juan Martin-Serrano,(juan.martin_serrano@kcl.ac.uk)

Rupture of the nuclear envelope (NE) during interphase is thought to be an infrequent event in healthy cells. Two papers recently published in Science describe the transient disruption of the NE continuity in cells migrating through confined spaces, and uncover an essential role for the Endosomal Sorting Complex Required for Transport (ESCRT) machinery in the resealing of these nuclear discontinuities.


10.1038/cr.2016.52

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