Volume 26, No 8, Aug 2016

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 26 Issue 8, August 2016: 859-860

RESEARCH HIGHLIGHTS

Inflammasomes: Intracellular detection of extracellular bacteria

Petr Broz¹

¹Focal Area Infection Biology, Biozentrum, University of Basel, Basel, Switzerland Correspondence: petr.broz@unibas.ch

The non-canonical inflammasome triggers host cell death and inflammation upon recognition of cytosolic LPS. A recent report in Cell now shows that Outer Membrane Vesicles (OMVs) of extracellular Gram-negative bacteria can deliver LPS into the host cell cytosol.

10.1038/cr.2016.67

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