Volume 26, No 8, Aug 2016

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 26 Issue 8, August 2016: 863-864

RESEARCH HIGHLIGHTS

Metabolic control of asyMYCtric division

Mytrang H Do^1,2 and Ming O Li¹

¹Immunology Program, Memorial Sloan Kettering Cancer Center, New York, NY 10065, USA
²Weill Cornell/Rockefeller/Sloan Kettering Tri-Institutional MD-PhD Program, New York, NY 10065, USA Correspondence: Ming O Li,(lim@mskcc.org)

Asymmetric division in CD8 T cells produces two daughter cells expressing different levels of c-Myc with distinct metabolic profiles. Manipulating this asymmetric partitioning of c-Myc skews T cell responses and potentially allows the development of more effective vaccines and cancer immunotherapies.

10.1038/cr.2016.60

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