Volume 26, No 9, Sep 2016

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 26 Issue 9, September 2016: 973-974

RESEARCH HIGHLIGHTS

Closing the gap: astrocytes and brain metastasis

Gino B Ferraro¹, David P Kodack¹, Vasileios Askoxylakis¹ and Rakesh K Jain¹

¹Edwin L. Steele Laboratory, Department of Radiation Oncology, Massachusetts General Hospital and Harvard Medical School, Boston, MA 02114, USA Correspondence: Rakesh K Jain, E-mail: jain@steele.mgh.harvard.edu

Astrocytes are emerging as essential regulators of brain metastasis progression. In a current issue of Nature, Chen et al. identify a novel mechanism of astrocyte-carcinoma interaction and exploit vulnerabilities therein to slow brain metastatic growth in pre-clinical models.

10.1038/cr.2016.96

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