Volume 26, No 10, Oct 2016

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 26 Issue 10, October 2016: 1169-1172

LETTERS TO THE EDITOR

Artemisinin derivatives prevent obesity by inducing browning of WAT and enhancing BAT function

Ping Lu¹, Fu-chuang Zhang², Shu-wen Qian¹, Xi Li¹, Zhao-meng Cui¹, Yong-jun Dang¹ and Qi-qun Tang^1,2

¹Key Laboratory of Metabolism and Molecular Medicine, the Ministry of Education; Department of Biochemistry and Molecular Biology, Fudan University Shanghai Medical College, Shanghai 200032, China
²Institute of Stem Cell Research and Regenerative Medicine, Institutes of Biomedical Sciences, Fudan University, Shanghai 200032, China Correspondence: Qi-qun Tang, Tel: 86-21-54237198 E-mail: qqtang@shmu.edu; Yong-jun Dang,(yongjundang@fudan.edu.cn)

Obesity and its related disorders have become a global pandemic1. Obesity leads to multiple chronic morbidities such as fatty liver, type 2 diabetes and cardiovascular diseases, and even increases the risk of several cancers. Five drugs have been approved by the Food and Drug Administration (FDA) for long-term weight management; however, there is still a long way to go before achieving satisfactory clinical outcome due to modest efficacy and unfavorable side effects2.

10.1038/cr.2016.108

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