Volume 26, No 11, Nov 2016

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 26 Issue 11, November 2016: 1178-1179

RESEARCH HIGHLIGHTS

A new edge to immune surveillance by the neural system

Jochem H Bernink¹, Hergen Spits¹ and Wouter J de Jonge²

¹Department of Experimental Immunology, Academic Medical Center at the University of Amsterdam, Amsterdam, the Netherlands
²Tytgat Institute for liver and intestinal research, Academic Medical Center at the University of Amsterdam, Amsterdam, the Netherlands Correspondence: Hergen Spits,(hergen.spits@amc.uva.nl)

A recent paper published in Nature demonstrates a multifaceted relation between enteric glial cells (EGC), intestinal epithelia, and ILC3, via the EGC release of neurotrophic factors, a structurally related group of ligands within the TGF-β superfamily of signaling molecules and IL-22 produced by ILC3.

10.1038/cr.2016.107

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