Volume 27, No 8, Aug 2017
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 27 Issue 8, August 2017: 959-960
RESEARCH HIGHLIGHTS
Cardiomyocyte proliferation: remove brakes and push accelerators
Lingjuan He1 and Bin Zhou1,2
1The State Key Laboratory of Cell Biology, CAS Center for Excellence in Molecular Cell Science, Shanghai Institute of Biochemistry and Cell Biology, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Shanghai 200031, China
2School of Life Science and Technology, ShanghaiTech University, Shanghai 201210, China
Correspondence: Bin Zhou,(zhoubin@sibs.ac.cn)
Adult mammalian hearts cannot repair by themselves after injury due to limited proliferation of cardiomyocytes; removal of cell cycle blocker and/or addition of drugs that boost proliferation of cardiomyocytes provide potential means to cardiac regeneration. Three publications that appeared recently in Nature and Cell Research now provide new hope to the treatment of heart injuries.
10.1038/cr.2017.91
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