Volume 27, No 8, Aug 2017

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 27 Issue 8, August 2017: 965-966

RESEARCH HIGHLIGHTS

It takes two to transport via an elevator

Bernadette Byrne¹

¹Department of Life Sciences, Imperial College London, London SW7 2AZ, UK Correspondence: Bernadette Byrne,(b.byrne@imperial.ac.uk)

Membrane transporter proteins are critical for cellular uptake and export of molecules, and are reported to function by a number of different molecular mechanisms. The new occluded state structure of the uracil transporter, UraA, from Escherichia coli, reveals that both coordinated movement of the two domains of a single protomer together with dimer formation are important for transport activity.

10.1038/cr.2017.89

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