Volume 27, No 11, Nov 2017

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 27 Issue 11, November 2017: 1307-1308

RESEARCH HIGHLIGHTS

tsRNAs: new players in mammalian retrotransposon control

Yunfang Zhang¹, Junchao Shi¹ and Qi Chen¹

¹Department of Physiology and Cell Biology, University of Nevada, Reno School of Medicine, NV 89512, USA Correspondence: Qi Chen(cqi@med.unr.edu)

A recent study led by Professor Rob Martienssen in Cell showed that 3′-tRNA-derived small RNAs can suppress long terminal repeat retrotransposon activity in mammalian cells by mechanisms independent of DNA-associated epigenetic marks, suggesting how the genome may defend itself from retrotransposon invasion during epigenetic reprogramming.

10.1038/cr.2017.109

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