Volume 27, No 12, Dec 2017

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 27 Issue 12, December 2017: 1401-1402

RESEARCH HIGHLIGHTS

A circular twist on microRNA regulation

Marco Bezzi¹, Jlenia Guarnerio¹ and Pier Paolo Pandolfi¹

¹Cancer Research Institute, Beth Israel Deaconess Cancer Center, Department of Medicine and Pathology, Beth Israel Deaconess Medical Center, Harvard Medical School, Boston, MA 02215, USA Correspondence: Pier Paolo Pandolfi,(ppandolf@bidmc.harvard.edu)

Circular RNAs (circRNAs) are a novel class of RNA whose physiological function has yet to be investigated. A recent publication in Science provides the first evidence of the biological relevance of a circRNA in an in vivo model and unveils an unexpected twist on their crosstalk with miRNAs.

10.1038/cr.2017.136

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