Volume 27, No 12, Dec 2017

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 27 Issue 12, December 2017: 1407-1408

RESEARCH HIGHLIGHTS

Fine-tuning type I IFN signaling: A new chapter in the IFN saga

Hideyuki Yanai¹ and Tadatsugu Taniguchi¹

¹Department of Molecular Immunology, Institute of Industrial Science, The University of Tokyo and Max Planck-The University of Tokyo Center for Integrative Inflammology, Komaba 4-6-1, Meguro-ku, Tokyo 153-8505, Japan Correspondence: Tadatsugu Taniguchi,(tada@m.u-tokyo.ac.jp)

Type I interferon (IFN) signaling is critical for intracellular antimicrobial programmes, affecting both innate and adaptive immune responses. The paper recently published in Cell demonstrates a new regulatory mechanism of the type I IFN signaling pathway by histone-lysine N-methyltransferase SETD2.

10.1038/cr.2017.118

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