Volume 28, No 2, Feb 2018

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 28 Issue 2, February 2018: 141-142

RESEARCH HIGHLIGHTS

Bad germs are trapped

Liman Zhang¹, Hao Wu1

¹Department of Biological Chemistry and Molecular Pharmacology, Harvard Medical School, and Program in Cellular and Molecular Medicine, Boston Children’s Hospital, Boston, MA 02115, USA Correspondence: Hao Wu(wu@crystal.harvard.edu)

Activation of the NAIP/NLRC4 inflammasomes initiates inflammatory
responses against bacterial invasion. Two recent reports described the cryo-EM structure of the flagellin/ NAIP5 complex, providing important insights into the mechanism of bacterial sensing by innate immunity.

10.1038/cr.2018.5

FULL TEXT | PDF

Browse 1766