Volume 28, No 6, Jun 2018
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 28 Issue 6, June 2018: 611-612
RESEARCH HIGHLIGHTS
Aberrant erythropoiesis fuels tumor growth
Kyohei Nakamura 1 and Mark J. Smyth 1
1Immunology in Cancer and Infection Laboratory, QIMR Berghofer Medical Research Institute, Herston 4006 QLD, Australia
Correspondence: Correspondence: Mark J. Smyth (mark.smyth@qimrberghofer.edu.au)
Tumor-induced aberrant myelopoiesis is known to induce immunosuppressive myeloid cells in cancer patients. Han et al. reveal that tumor-induced spleen erythroblast-like cells, called Ter-cells, promote tumor growth via secretion of a neurotropic factor, artemin, providing evidence that altered erythropoiesis also directly contributes to tumor progression.
https://doi.org/10.1038/s41422-018-0047-1
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