Volume 28, No 9, Sep 2018

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 28 Issue 9, September 2018: 875-876

RESEARCH HIGHLIGHTS

m6A reader suppression bolsters HSC expansion

Xinxin Huang ¹ and Hal E. Broxmeyer ¹

¹Department of Microbiology and Immunology, Indiana University School of Medicine, Indianapolis, IN, USA Correspondence: Correspondence: Hal E. Broxmeyer (hbroxmey@iupui.edu)

The functional importance of N 6 -methyladenosine (m 6 A) modification in human health and disease has recently entered the research spotlight. In a recent paper published in Cell Research , Li et al. report a remarkable finding that deficiency in m 6 A reader Ythdf2 results in a striking expansion of mouse and human hematopoietic stem cells.

https://doi.org/10.1038/s41422-018-0081-z

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