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Volume 28, No 10, Oct 2018

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 28 Issue 10, October 2018: 963-964

RESEARCH HIGHLIGHTS

Guiding a mutator in antibody diversification

Ming Tian 1 and Frederick W. Alt 1

1Boston Children’s Hospital, Harvard Medical School, HHMI, Boston, MA 02115, USA
Correspondence: Correspondence: Ming Tian (Ming_Tian@hms.harvard.edu)

Activation Induced Cytidine Deaminase is a mutator that is essential for antibody diversification. A new study, recently reported in Cell Research , provides insights into the mechanism that guides the mutator to physiological targets.


https://doi.org/10.1038/s41422-018-0085-8

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