Volume 28, No 11, Nov 2018

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 28 Issue 11, November 2018: 1045-1045

RESEARCH HIGHLIGHTS

A new STAT3 function: pH regulation

Yuxin Wang ¹ and George R. Stark ¹

¹Department of Cancer Biology, Lerner Research Institute, Cleveland Clinic, Cleveland, OH 44195, USA
Correspondence: Correspondence: George R. Stark (STARKG@ccf.org)

In a recent paper published in Cell Research, Liu et al. describe a novel function of STAT3, a classical oncogene, on lysosomes to regulate pH by interacting with the vacuolar H+-ATPase. This finding suggests a new anti-cancer strategy by limiting this function.

https://doi.org/10.1038/s41422-018-0098-3

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