Volume 29, No 1, Jan 2019

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 29 Issue 1, January 2019: 1-3

RESEARCH HIGHLIGHTS

Engineering 3D genome organization

Xiaowen Lyu ¹ and Victor G. Corces ¹

¹Department of Biology, Emory University, Atlanta, GA 30322, USA
Correspondence: Correspondence: Victor G. Corces (vgcorces@gmail.com)

The causal relationship between nuclear position and gene expression remains under intense debate. Qi and colleagues developed the CRISPR-GO system to efficiently reposition any genomic sequence to a specific nuclear compartment and examine its effect on transcription.

https://doi.org/10.1038/s41422-018-0116-5

FULL TEXT | PDF

Browse 1130