Volume 29, No 2, Feb 2019

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 29 Issue 2, February 2019: 91-92

RESEARCH HIGHLIGHTS

mRNA acetylation: a new addition to the epitranscriptome

P. Cody He ^1,2,3 and Chuan He ^1,2,3

¹ Department of Chemistry, Department of Biochemistry and Molecular Biology, Institute for Biophysical Dynamics, The University of Chicago, Chicago, IL 60637, USA; ²Committee on Immunology, The University of Chicago, Chicago, IL 60637, USA and ³Howard Hughes Medical Institute, The University of Chicago, Chicago, IL 60637, USA
Correspondence: Chuan He (chuanhe@uchicago.edu)

The epitranscriptome, comprising a diverse set of post-transcriptional chemical modifications of mRNA, is an important regulator of gene expression. In a recent study, Arango and colleagues identify acetylation of cytidine (ac 4 C) as a new mRNA modification that increases the stability and translation efficiency of transcripts.

https://doi.org/10.1038/s41422-018-0135-2

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