Volume 29, No 5, May 2019

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 29 Issue 5, May 2019: 343-344

RESEARCH HIGHLIGHTS

Linking vitamin B12 and a trembling disorder

Ralph Green¹ and Chadwick W. Christine²

¹Department of Pathology and Laboratory Medicine, University of California, Davis, Sacramento, CA 95817, USA and ²Department of Neurology, University of California, San Francisco, San Francisco, CA 94158, USA
Correspondence: Ralph Green (rgreen@ucdavis.edu)

Hyperactivity of LRRK2, a multifunctional serine/threonine protein kinase, is central to Parkinson’s disease pathogenesis. Vitamin B12 turns out to be a potent inhibitor of its undesirable activity.

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