Volume 29, No 7, Jul 2019

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 29 Issue 7, July 2019: 514-515

RESEARCH HIGHLIGHTS

Chemical choreography of germinal center B-cell migration

Vu N. Ngo¹ and Markus Müschen ¹

¹ Department of Systems Biology and City of Hope Comprehensive Cancer Center, Monrovia, CA 91016, USA
Correspondence: Markus Müschen (mmuschen@coh.org)

Germinal center (GC) B cells are confined at the center of the B cell follicles by a mechanism that is only partially understood. Using biochemical fractionation and mass spectrometry, Lu and colleagues now identify a novel cue for GC B-cell positioning and define the gradient formation mechanism for this new ligand.

https://doi.org/10.1038/s41422-019-0170-7

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