Volume 29, No 11, Nov 2019

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 29 Issue 11, November 2019: 877-878

RESEARCH HIGHLIGHTS

Nociceptor nerves set the stage for skin immunity

Felipe A. Pinho-Ribeiro¹ and Isaac M. Chiu ¹

¹ Department of Immunology, Harvard Medical School, 77 Avenue Louis Pasteur, Boston, MA 02115, USA
Correspondence: Isaac M. Chiu (Isaac_chiu@hms.harvard.edu)

Nociceptor sensory neurons densely innervate the skin and detect potentially damaging stimuli. Cohen and colleagues show that nociceptor neurons drive local axonal reflexes that build anticipatory type 17 skin immune responses to protect the host against pathogens.

https://doi.org/10.1038/s41422-019-0240-x

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