Volume 30, No 5, May 2020

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 30 Issue 5, May 2020: 372-373

RESEARCH HIGHLIGHTS

A separation that’s for the best: coming together at the PAS

Wayne D. Hawkins^1,2 , Daniel J. Klionsky^1,2,*

¹Life Sciences Institute, University of Michigan, Ann Arbor, MI 48109, USA
²Department of Molecular, Cellular and Developmental Biology, University of Michigan, Ann Arbor, MI 48109, USA
Correspondence: Daniel J. Klionsky(klionsky@umich.ed)

The phagophore assembly site is an organizing center for several proteins that facilitate the initiation and expansion of autophagic membranes. Fujioka and colleagues report that this structure is not a rigid complex but, instead, a liquid-like condensate, the stability of which relies heavily on the interactions of the disordered protein Atg13.

https://doi.org/10.1038/s41422-020-0297-6

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