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Volume 30, No 5, May 2020

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 30 Issue 5, May 2020: 374-375

RESEARCH HIGHLIGHTS

Proteasome phase separation: a novel layer of quality control

Victoria Cohen-Kaplan , Ido Livneh , Aaron Ciechanover*

Technion Integrated Cancer Center, The Rappaport Faculty of Medicine and Research Institute, Technion-Israel Institute of Technology, 3109602 Haifa, Israel
Correspondence: Aaron Ciechanover(aaroncie@technion.ac.il)

Maintenance of the quality control of the cellular proteome involves several pathways and a variety of transient and interchangeable assemblies. A recently discovered membraneless foci that contain — among several components — the 26S proteasome complex and that are generated in response to a proteotoxic stress, is the recent addition to this ever-growing list.


https://doi.org/10.1038/s41422-020-0306-9

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