Volume 30, No 7, Jul 2020

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 30 Issue 7, July 2020: 562-563

RESEARCH HIGHLIGHTS

ILC transdifferentiation: roles in cancer progression

Maryam Ghaedi¹ , Pamela S. Ohashi^1,2,*

¹Princess Margaret Cancer Centre, University Health Network, Toronto, ON, Canada
²Department of Immunology, University of Toronto, Toronto, ON, Canada
Correspondence: Pamela S. Ohashi(Pam.Ohashi@uhnresearch.ca)

Innate lymphoid cells (ILCs) play key roles in determining the outcome of immune responses and their roles in shaping tumor immunity have begun to be deciphered. Wang et al. demonstrate that dynamic conversions of ILC subsets and functions might promote colorectal cancer (CRC) progression; hence, targeting ILCs may present a potential novel approach to immunotherapy.

https://doi.org/10.1038/s41422-020-0326-5

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