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Submit Manuscript Volume 30, No 10, Oct 2020
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 30 Issue 10, October 2020: 936-939 |
A COVID-19 mRNA vaccine encoding SARS-CoV-2 virus-like particles induces a strong antiviral-like immune response in mice
Jing Lu1 , Guoliang Lu1 , Shudan Tan1 , Jia Xia2 , Hualong Xiong3 , Xiaofei Yu4 , Qingqing Qi4 , Xiang Yu5 , Li Li1 , Hang Yu6 , Ningshao Xia3 , Tianying Zhang3,* , Yingjie Xu5,* , Jinzhong Lin1,*
1State Key Laboratory of Genetic Engineering, School of Life Sciences, Zhongshan Hospital, Fudan University, Shanghai 200438, ChinaDear Editor,
Since the beginning of this century, humanity has been struck three times by the coronavirus outbreak. The most recent one is caused by the SARS-CoV-2 virus, which was first reported in January 2020 and spread rapidly worldwide, developing into a global coronavirus disease pandemic coded COVID-19.1 By July 28, 2020, SARS-CoV-2 has caused over sixteen million COVID-19 cases worldwide and 650,805 deaths.2 Such a grave situation has made the development of a COVID-19 vaccine imperative and urgent.3
https://doi.org/10.1038/s41422-020-00392-7