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Submit Manuscript Volume 30, No 10, Oct 2020
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 30 Issue 10, October 2020: 829-830
RNA and the PIEZO force sensor
David J. Beech* , Laeticia Lichtenstein
School of Medicine, LIGHT Building, University of Leeds, Clarendon Way, Leeds LS2 9JT, UKThe discovery of the PIEZO force-sensing ion channels was an important advance in recent years, leading to exciting new knowledge and fields of inquiry. An interesting article published by Sugisawa et al. in Cell unexpectedly suggests PIEZO1 channels as RNA rather than force sensors in enterochromaffin cells, with important implications for microbiome response and gut motility mediated by 5-HT.
https://doi.org/10.1038/s41422-020-00413-5