Volume 31, No 1, Jan 2021

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 31 Issue 1, January 2021: 3-4

RESEARCH HIGHLIGHTS

Water quality check: macrophages setting the standards

Camille Blériot¹ , Zhaoyuan Liu² , Florent Ginhoux^2,3,4,*

¹Inserm U1015, Gustave Roussy, Villejuif 94800, France
²Shanghai Institute of Immunology, Shanghai Jiao Tong University School of Medicine, Shanghai 200025, China
³Singapore Immunology Network (SIgN), Agency for Science, Technology and Research (A*STAR), 8A Biomedical Grove, Immunos Building #3-4, Biopolis, Singapore 138648, Singapore
⁴Translational Immunology Institute, SingHealth Duke-NUS Academic Medical Centre, Singapore 169856, Singapore
Correspondence: Florent Ginhoux(Florent_Ginhoux@immunol.a-star.edu.sg)

In a recent study published in Cell, Chikina et al. uncovered a new mechanism by which colonic macrophages perform quality check of fluids absorbed by colonic epithelial cells. This critical function allows the maintenance of barrier integrity by avoiding intoxication with fungal toxins and the resulting life-threatening risk of colonocyte apoptosis.

https://doi.org/10.1038/s41422-020-00429-x

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