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Volume 31, No 3, Mar 2021

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 31 Issue 3, March 2021: 245-246

RESEARCH HIGHLIGHTS

Gephyrin: a scaffold that builds a phase at the inhibitory postsynapses

Christian Hoffmann , Dragomir Milovanovic*

Laboratory of Molecular Neuroscience, German Center for Neurodegenerative Diseases (DZNE), 10117 Berlin, Germany
Correspondence: Dragomir Milovanovic(dragomir.milovanovic@dzne.de)

The scaffolding protein gephyrin is a core component of many inhibitory synapses. Bai and colleagues now show that phase separation of gephyrin with the subunits of both glycine and GABA receptors underlies the formation of postsynaptic sheets at the inhibitory synapses.


https://doi.org/10.1038/s41422-020-00440-2

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