Volume 31, No 4, Apr 2021

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 31 Issue 4, April 2021: 375-376

RESEARCH HIGHLIGHTS

Remembering past infections: training exercise for gut microbes

Samuel Philip Nobs¹ , Eran Elinav^1,2,*

¹Immunology Department, Weizmann Institute of Science, Rehovot, Israel
²Cancer-Microbiome Division, Deutsches Krebsforschungszentrum (DKFZ), Heidelberg, Germany
Correspondence: Eran Elinav(eran.elinav@weizmann.ac.il)

Colonization resistance is considered a key defense strategy against infection with pathogens. In a recent study published in Cell , Stacy et al. identify and dissect a novel, active, microbiome-mediated molecular resistance mechanism; upon pathogenic infection, the “memorizing” microbiome develops a capacity of secreting taurine to restrict pathogen respiration, thereby inducing infection resistance to subsequent exposures.

https://doi.org/10.1038/s41422-021-00481-1

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