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Volume 31, No 6, Jun 2021

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 31 Issue 6, June 2021: 603-604

RESEARCH HIGHLIGHTS

3D genome encoded by LINE and SINE repeats

Zhengyu Liang , Xiang-Dong Fu*

Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093-0651, USA
Correspondence: Xiang-Dong Fu(xdfu@ucsd.edu)

Retrotransposons are embedded in distinct genomic regions, many giving rise to repeat-enriched transcripts. In a recent paper of Cell Research , Lu et al. show that L1 and B1 retrotransposons are separately clustered in mammalian genomes where L1 transcription and transcripts play a vital role in orchestrating the formation of 3-dimensional genome.


https://doi.org/10.1038/s41422-021-00485-x

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