Advanced Search
Submit Manuscript Volume 31, No 6, Jun 2021
ISSN: 1001-0602
EISSN: 1748-7838 2018
impact factor 17.848*
(Clarivate Analytics, 2019)
Volume 31 Issue 6, June 2021: 603-604
3D genome encoded by LINE and SINE repeats
Zhengyu Liang , Xiang-Dong Fu*
Department of Cellular and Molecular Medicine, University of California, San Diego, La Jolla, CA 92093-0651, USARetrotransposons are embedded in distinct genomic regions, many giving rise to repeat-enriched transcripts. In a recent paper of Cell Research , Lu et al. show that L1 and B1 retrotransposons are separately clustered in mammalian genomes where L1 transcription and transcripts play a vital role in orchestrating the formation of 3-dimensional genome.
https://doi.org/10.1038/s41422-021-00485-x