Volume 31, No 5, May 2021

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 31 Issue 5, May 2021: 493-494

RESEARCH HIGHLIGHTS

Developments in pluripotency: a new formative state

Stefan H. A. Hoogland , Hendrik Marks^*

Faculty of Science, Department of Molecular Biology, Radboud Institute for Molecular Life Sciences (RIMLS), Radboud University, Nijmegen 6525GA, The Netherlands
Correspondence: Hendrik Marks(h.marks@ncmls.ru.nl)

During development, mouse embryonic cells progress in around 4 days from a naïve to a primed pluripotent state. A recent study in Cell Research by Wang and colleagues reports the in vitro capture of an intermediate pluripotent state, represented by so-called formative pluripotent stem cells, revealing the dynamic nature of the progression of pluripotency.

https://doi.org/10.1038/s41422-021-00494-w

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