Volume 31, No 8, Aug 2021

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 31 Issue 8, August 2021: 832-833

RESEARCH HIGHLIGHTS

Host genetics, the microbiome & behaviour—a ‘Holobiont’ perspective

Jatin Nagpal¹ , John F. Cryan^1,2,*

¹APC Microbiome Ireland, University College Cork, Cork, Ireland
²Department of Anatomy and Neuroscience, University College Cork, Cork, Ireland
Correspondence: John F. Cryan(j.cryan@ucc.ie)

Complex behaviors in genetic neurological disorders have traditionally been viewed through the prism of genetic influences on brain development and function. In a recent study published in Cell , Costa-Mattioli and colleagues make a compelling argument that the gut microbiome and the host genes can interdependently regulate different behaviors in a genetic mouse model of autism.

https://doi.org/10.1038/s41422-021-00512-x

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