Volume 32, No 2, Feb 2022

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 32 Issue 2, February 2022: 119-138

ORIGINAL ARTICLES

A new type of ERGIC–ERES membrane contact mediated by TMED9 and SEC12 is required for autophagosome biogenesis

Shulin Li^1,2,3 , Rui Yan⁴ , Jialu Xu^2,3,5 , Shiqun Zhao^6,7 , Xinyu Ma^1,2,3 , Qiming Sun⁸ , Min Zhang^1,2,3 , Ying Li^1,2,3 , Jun-Jie Gogo Liu^2,3,5 , Liangyi Chen^6,7 , Sai Li^2,3,5 , Ke Xu⁴ , Liang Ge^1,2,3,*

¹State Key Laboratory of Membrane Biology, Beijing, China
²Tsinghua-Peking Center for Life Sciences, Beijing, China
³School of Life Sciences, Tsinghua University, Beijing, China
⁴Department of Chemistry, University of California, Berkeley, CA, USA
⁵Beijing Advanced Innovation Center for Structural Biology, Beijing, China
⁶Beijing Key Laboratory of Cardiometabolic Molecular Medicine, Institute of Molecular Medicine, Peking University, Beijing, China
⁷National Center for Nanoscience and Technology, Beijing, China
⁸Department of Biochemistry, Department of Cardiology of Second Affiliated Hospital, Zhejiang University School of Medicine, Hangzhou, Zhejiang, China
Correspondence: Liang Ge(liangge@mail.tsinghua.edu.cn)

Under stress, the endomembrane system undergoes reorganization to support autophagosome biogenesis, which is a central step in autophagy. How the endomembrane sys

https://doi.org/10.1038/s41422-021-00563-0

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