Volume 32, No 1, Jan 2022

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 32 Issue 1, January 2022: 1-2

RESEARCH HIGHLIGHTS

Novel SARS-CoV-2 receptors: ASGR1 and KREMEN1

Markus Hoffmann^1,2,* , Stefan Pöhlmann^1,2,*

¹Infection Biology Unit, German Primate Center, Göttingen, Germany
²Faculty of Biology and Psychology, Georg-August-University Göttingen, Göttingen, Germany
Correspondence: Markus Hoffmann(mhoffmann@dpz.eu)Stefan Pöhlmann(spoehlmann@dpz.eu)

The interaction of the SARS-CoV-2 spike protein with the cellular receptor ACE2 is believed to be essential for viral entry into host cells. In a recent paper published in Cell Research, Gu and colleagues report that ASGR1 and KREMEN1 can also serve as SARS-CoV-2 receptors and might impact viral target cell range and antibody-mediated neutralization.

https://doi.org/10.1038/s41422-021-00603-9

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