Volume 32, No 6, Jun 2022

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 32 Issue 6, June 2022: 511-512

RESEARCH HIGHLIGHTS

Nuclear tetraspanin 8 promotes breast cancer progression

Kadellyn Sandoval¹ , William A. Weiss^1,2,3,4,*

¹Graduate Program in Biomedical Sciences, University of California, San Francisco, CA, USA
²Department of Neurology, University of California, San Francisco, CA, USA
³Helen Diller Family Comprehensive Cancer Center, University of California, San Francisco, CA, USA
⁴Departments of Pediatrics and Neurological Surgery, University of California, San Francisco, CA, USA
Correspondence: William A. Weiss(waweiss@gmail.com)

In a recent work in Cell Research , Lu et al. demonstrate that nuclear translocation of the cell surface glycoprotein tetraspanin 8 enhances STAT3 signaling and breast cancer progression. A blocking antibody led to partial tumor control in vitro and in vivo.

https://doi.org/10.1038/s41422-022-00657-3

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