Volume 32, No 10, Oct 2022

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 32 Issue 10, October 2022: 873-874

RESEARCH HIGHLIGHTS

Profiling spatial gene activity in marmoset embryos

Guangdun Peng¹ , Patrick P. L. Tam^2,*

¹Center for Cell Lineage and Development, CAS Key Laboratory of Regenerative Biology, Guangdong Provincial Key Laboratory of Stem Cell and Regenerative Medicine, GIBHHKU Guangdong-Hong Kong Stem Cell and Regenerative Medicine Research Centre, Guangzhou Institutes of Biomedicine and Health, Chinese Academy of Sciences, University of Chinese Academy of Sciences, Guangzhou, Guangdong, China
²Embryology Research Unit, Children’s Medical Research Institute, and School of Medical Sciences, Faculty of Medicine and Health, University of Sydney, Sydney, NSW 2145, Australia
Correspondence: Patrick P. L. Tam(ptam@cmri.org.au)

Spatial transcriptomics of the marmoset embryo unveils insights into the molecular landscape of post-implantation development and provides a reference dataset of cell and tissue identity and the mechanistic attributes of germ layer formation. The knowledge gains of the developmental coordinates of early gastrulation point to the utility of this non-human primate for modeling post-implantation development of human embryos.

https://doi.org/10.1038/s41422-022-00703-0

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