Volume 32, No 10, Oct 2022

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 32 Issue 10, October 2022: 949-952

LETTERS TO THE EDITOR

Omicron-specific mRNA vaccine elicits potent immune responses in mice, hamsters, and nonhuman primates

Yi Wu^1,2,† , Yanqiong Shen^2,† , Namei Wu^1,2,† , Xinghai Zhang^3,† , Shaohong Chen^3,4 , Chang Yang^1,2 , Junhui Zhou^3,4 , Yan Wu³ , Da Chen⁵ , Li Wang² , Chao Wang⁵ , Huajun Zhang^3,* , Ninuo Xia^2,* , Sandra Chiu^2,* , Yucai Wang^1,2,6,*

¹Department of Radiology, The First Affiliated Hospital of USTC, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
²School of Basic Medical Sciences, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
³State Key Laboratory of Virology, Wuhan Institute of Virology, Center for Biosafety MegaScience, Chinese Academy of Sciences, Wuhan, Hubei, China
⁴University of Chinese Academy of Sciences, Beijing, China
⁵MOE Key Laboratory for Cellular Dynamics, Division of Life Sciences and Medicine, University of Science and Technology of China, Hefei, Anhui, China
⁶RNAlfa Biotech, Hefei, Anhui, China
^†These authors contributed equally: Yi Wu, Yanqiong Shen, Namei Wu, Xinghai Zhang
Correspondence: Huajun Zhang(hjzhang@wh.iov.cn)Ninuo Xia(nxia007@ustc.edu.cn)Sandra Chiu(qiux@ustc.edu.cn)Yucai Wang(yucaiwang@ustc.edu.cn)

Dear Editor,

Severe acute respiratory syndrome coronavirus 2 (SARS-CoV-2) has infected more than 400 million people globally, resulting in millions of deaths.1 As the virus evolves, a new variant, designated as “Omicron” by the World Health Organization (SARS-CoV-2 variant B.1.1.529), has led to a massive resurgence of COVID-19 cases in many regions.2 The Omicron variant is highly contagious, with a significant transmission advantage compared to prior variants. Currently, Omicron represents ~95% of the new infections in the US, Europe, Brazil, South Africa, and elsewhere.3,4,5

https://doi.org/10.1038/s41422-022-00706-x

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