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Volume 32, No 12, Dec 2022

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 32 Issue 12, December 2022: 1042-1043


Live cold to grow old? Thermogenesis to fight cancer

Henning T. Langer1 , Lewis C. Cantley2 , Marcus D. Goncalves1,*

1Division of Endocrinology, Department of Medicine, Weill Cornell Medicine, New York, NY, USA
2Department of Cancer Biology, Dana-Farber Cancer Institute, Boston, MA, USA
Correspondence: Marcus D. Goncalves(

A drop in ambient temperature induces systemic changes in glucose metabolism that enable thermogenesis. A recent article by Seki and colleagues explored the potential of cold exposure and brown fat activation to stop tumor growth.


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