Volume 33, No 3, Mar 2023

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 33 Issue 3, March 2023: 193-194

RESEARCH HIGHLIGHTS

Objection non-responsive! How maternal immune activation in pregnancy weakens subsequent microglial immune response

Thomas Blank^1,* , Marco Prinz^1,2,3,*

¹Institute of Neuropathology, Faculty of Medicine, University of Freiburg, Freiburg, Germany
²Center for NeuroModulation, Faculty of Medicine, University of Freiburg, Freiburg, Germany
³Signalling Research Centers BIOSS and CIBSS, University of Freiburg, Freiburg, Germany
Correspondence: Thomas Blank(thomas.blank@uniklinik-freiburg.de)Marco Prinz(marco.prinz@uniklinik-freiburg.de)

Virus-like immunological stress during pregnancy diminishes subsequent microglia reactivity, elevating astrocyte inflammatory state and reducing synaptic activity in medium spiny neurons of the ventral striatum.

https://doi.org/10.1038/s41422-022-00756-1

FULL TEXT | PDF

Browse 581