Volume 33, No 3, Mar 2023

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 33 Issue 3, March 2023: 195-196

RESEARCH HIGHLIGHTS

An exploitable Achilles heel of MITF?

Carolina Silva^1,2 , Ze’ev A. Ronai^1,*

¹Cancer Center, Sanford Burnham Prebys Medical Discovery Institute, La Jolla, CA, USA
²The University of São Paulo, São Paulo, Brazil
Correspondence: Ze’ev A. Ronai(zeev@ronailab.net)

Microphthalmia-associated transcription factor (MITF) has been implicated in melanoma development and progression. In a study published in Cell Research, Liu et al. suggest that inhibition of MITF via targeting of its dimer interface may provide a novel therapeutic modality.

https://doi.org/10.1038/s41422-022-00762-3

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