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Volume 33, No 5, May 2023

ISSN: 1001-0602 
EISSN: 1748-7838 2018 
impact factor 17.848* 
(Clarivate Analytics, 2019)

Volume 33 Issue 5, May 2023: 339-340

RESEARCH HIGHLIGHTS

How pain sensors make the gut weep

Nathalie Stakenborg , Yaping Xue , Guy Boeckxstaens*

Center of Intestinal Neuro-immune interaction, Translational Research Center for GI Disorders (TARGID), Department of Chronic Diseases, Metabolism and Ageing, KU Leuven, Leuven, Belgium
Correspondence: Guy Boeckxstaens(guy.boeckxstaens@kuleuven.be)

Nociceptors in the gut are widely known for transmitting pain signals to the spinal cord. Yang et al. now identified a novel microbiome-nociceptor-goblet cell crosstalk that protects the intestinal epithelial barrier by triggering mucus secretion.


https://doi.org/10.1038/s41422-022-00768-x

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